Skip main navigation

Turn up the volume!

"spines - enrichment taxi driver hippocampal volume conditioning/context/association "
3.5
Learning can be defined as “an adaptive change in behaviour resulting from experience”, and memory is the retention of learning. The ability of the brain to change in response to an experience is referred to as ‘neuronal plasticity’. So what are the plastic changes that occur in the brain when we learn something? Coming back to our analogy of a computer, where the hippocampus is the processor and the cortex is the hard drive, we need to consider how the hippocampus encodes information that can then be stored in the cortex. We know that our billions of neurons are connected by a million billion synapses, forming complex networks.
38.6
If the number of neurons in the adult brain does not change significantly over our lifetime, how is information encoded? It’s the changes in electrical activity of neurons and the way they communicate with each other that encodes patterns of information. At a gross level we know that learning a lot of information can increase the number of synapses. For instance a neuroimaging study showed that London taxi drivers who learn the road map of London, have a bigger hippocampus compared to an average person. In addition to new connections being formed, learning can alter the properties of existing synapses to encode information.
73.2
It is known that learning can increase both the amount of neurotransmitter released from the presynaptic cell and increase the number of neurotransmitter receptors in the post-synaptic cell. This means that for the same stimulation the synapse will communicate information more efficiently. You can imagine that following learning, a synapse that was whispering, starts to shout. So learning can ‘turn up the volume’ of our synaptic connections. So what is special about a learning stimulus compared to the normal communication between neurons? Where is the specificity? Are synapses constantly changing and turning up their volume? Well, it turns out that learning stimuli are very strong. For example, many synaptic connections with the same neuron will fire together, and repeatedly.
117.3
These learning stimuli trigger molecular mechanisms within neurons to change the synapses. For the past thirty years, molecular neuroscience research has been dominated by the study of these changes. If neuroscientists can better understand how synapses change when we learn, this may help to develop drugs that improve learning in people that have neurological disorders or neurodegeneration.
How does the brain encode information? What is the basis for learning and memory? In this section, Dr. Gareth Evans will explore these questions at the level of the synapse.
Here are some questions to consider while you’re watching the video. We’d be happy to hear from you in the comments once you’ve watched the video.
  • Are the changes made to synapses during learning permanent? Or will they return to the state before learning if not used much?
  • Will synaptic plasticity keep increasing the activity of synapses (how loud can a synapse shout?)
  • Does sleep have a role in learning and memory?
This article is from the free online

The Biology of Bugs, Brains, and Beasts

Created by
FutureLearn - Learning For Life

Our purpose is to transform access to education.

We offer a diverse selection of courses from leading universities and cultural institutions from around the world. These are delivered one step at a time, and are accessible on mobile, tablet and desktop, so you can fit learning around your life.

We believe learning should be an enjoyable, social experience, so our courses offer the opportunity to discuss what you’re learning with others as you go, helping you make fresh discoveries and form new ideas.
You can unlock new opportunities with unlimited access to hundreds of online short courses for a year by subscribing to our Unlimited package. Build your knowledge with top universities and organisations.

Learn more about how FutureLearn is transforming access to education