Skip main navigation

Which factor(s) impacts the loading dose ?

Which factor(s) impacts the loading dose? Volume, half-life, or clearance?

Continuing from the previous video, Prof. Brown specifies how a loading dose relates to the volume of distribution (V).

He shows the relationship between elimination and accumulation during a drug infusion, which is important for this lesson.

Can you tell which factor(s) impacts the loading dose for a patient? Is it the volume of distribution (V), clearance (CL), k, or half-life? This concept is explained further in two brain exercises in this video.

What do you think of the relationship between elimination and accumulation during a drug infusion? Please share your thoughts below.


Educator:

Prof. Daniel L. Brown


This article is from the free online

Clinical Pharmacokinetics: Dosing and Monitoring

Created by
FutureLearn - Learning For Life

Reach your personal and professional goals

Unlock access to hundreds of expert online courses and degrees from top universities and educators to gain accredited qualifications and professional CV-building certificates.

Join over 18 million learners to launch, switch or build upon your career, all at your own pace, across a wide range of topic areas.

Start Learning now