Skip main navigation

Overview of this week

What can you expect to learn from this week? Professor Daniel Brown is going to explain the topic: What Pharmacists Need to Know about Dosing Aminoglycosides and Vancomycin

Summary of Week 5:

1. The differences between time-dependent and concentration-dependent antibiotic killing.
2. Distinguish between AUC24 and AUIC.
3. Estimate vancomycin CL and identify the target values for vancomycin trough and AUIC.
4. Determine a vancomycin dosing regimen (loading dose, intermittent regimen or continuous infusion) based on CLCr, patient weight and severity of the infection.
5. How extended-interval dosing of aminoglycosides relates to concentration-dependent killing and a post-antibiotic effect.
6. How to use the Hartford nomogram and how to estimate aminoglycoside k and half-life.

We hope you enjoy.

This article is from the free online

Clinical Pharmacokinetics: Dosing and Monitoring

Created by
FutureLearn - Learning For Life

Reach your personal and professional goals

Unlock access to hundreds of expert online courses and degrees from top universities and educators to gain accredited qualifications and professional CV-building certificates.

Join over 18 million learners to launch, switch or build upon your career, all at your own pace, across a wide range of topic areas.

Start Learning now