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How to determine a Vancomycin dosing regimen based on AUIC?

How to determine a Vancomycin dosing regimen based on AUIC?

Prof. Brown uses an example to describe how to adjust Vancomycin dosing based on AUC (24hr).

We can understand AUC therapeutic targets for Vancomycin, including maximizing efficacy and minimizing nephrotoxicity.

He provides a dosing chart developed by Wanfang Hospital, which reveals the daily dose that should be given to a patient.

What is the relationship between dose, AUIC, and MIC? Please leave your answer below.

Do you find any dosing difference(s) between your hospital and Wanfang Hospital? And what is your opinion? Please share your opinion below.


Prof. Daniel L. Brown

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Clinical Pharmacokinetics: Dosing and Monitoring

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