Skip main navigation

New offer! Get 30% off one whole year of Unlimited learning. Subscribe for just £249.99 £174.99. New subscribers only. T&Cs apply

Find out more

Case study: Huntington’s disease

Case study: huntington's disease
Huntington's disease brain
Huntington’s disease (HD) is a disorder that someone is born with yet they often don’t experience symptoms until well into adulthood. It occurs when an individual has a mutated form of a single gene out of the 20-25,000 that humans have. Consequently, the individual’s cells produce an unusual form of a protein. This protein is normally important for function in various tissues throughout the body including the brain.

Within the brain it appears to be important for the normal functioning of neurones in particular parts of the brain which, therefore, leads to that person exhibiting some or all of a characteristic set of symptoms.

Your task:

  • What are the classical symptoms of HD?
  • What does this tell us about the brain regions most involved?
  • How does the abnormal protein affect the neurones?

© University of Birmingham
This article is from the free online

Good Brain, Bad Brain: Basics

Created by
FutureLearn - Learning For Life

Reach your personal and professional goals

Unlock access to hundreds of expert online courses and degrees from top universities and educators to gain accredited qualifications and professional CV-building certificates.

Join over 18 million learners to launch, switch or build upon your career, all at your own pace, across a wide range of topic areas.

Start Learning now