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Sand fly bite 

Note: this video has no sound. In this video we watch a female sand fly of the species Lutzomia longipalpis (most commonly found in South America), taking a blood meal …

The vector that spreads visceral leishmaniasis 

This section begins by introducing you to important features of sand flies and their lifecycles. Scientist and expert vector biologist Dr Matthew Rogers will guide you through these and help …

Week 2 Acknowledgements

Many thanks from the course team. Lead Educators: Vanessa Yardley, Simon Croft Coordination: Markela Koniordou Course content production: Markela Koniordou, Vanessa Yardley Course production: Video (VL diagnosis) production and filming: …

Summary of Week 2

What have we learned? During week 2 we have explored in more detail how visceral leishmaniais is recognised and confirmed and how it is treated. We have learned that there …

Practicalities to consider (check-list)

Previous steps have covered a wide range of topics, describing best practice in an ideal setting. As Dr Adera describes in Step 2.12, the diagnosis and treatment of VL can …

Visceral Leishmaniasis: Complex treatments

When it comes to “special” groups, safety during treatment of VL is crucial[1]. These groups usually relate to factors which will have a bearing on VL treatment such as immunosuppression, …

Diagnosis & treatment of PKDL

In this step, we visit a South Asian (Indian) perspective on the diagnosis and treatment of post- kala azar dermal leishmaniasis (PKDL) with two experts in the disease: Professor (Dr) …

Treatment of VL in the clinic

Treatment of visceral leishmaniasis in the clinic depends upon a number of factors. These range from the availability of the drug in the country concerned to the existence of resistance …

DAT demonstration video

Direct Agglutination Test (DAT) The DAT antigen consists of freeze-dried L. donovani promastigotes that are stained blue. Suspended in solution, the antigen is mixed with patient serum. If anti-Leishmania antibodies …

RDT demonstration video

Rapid rK39 antigen-based tests (RDTs) are based on the antigen rK39, a recombinant product of a 39 amino acid antigen encoded by a kinesin-like gene of the L. donovani complex. …

Methods of diagnosis

How can we diagnose visceral leishmaniasis? A number of different methods have been developed over the years but not all are suitable for routine use in the field or clinic[1]. …