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Understanding the synthesis of analogues and SARs

Me-Too Medicines The successful progress in treating several diseases has led to the development of a pharmaceutical industry with an estimated market of around £1 trillion (that is £1,000,000,000,000; to …

Non-beta-lactam antibiotics

To allow the treatment of bacteria with resistances to, for example, β-lactams, there is a need for a variety of antibiotic medicines with different structures and modes of action. Five …

An Introduction to Penicillin

Despite having been discovered almost 90 years ago, penicillins and related compounds, called cephalosporins, remain the most widely-used antibiotics in the world, accounting for nearly 60% of all total antibiotic …

Theories of smell – Molecule Shape and Smell

Vibrational theory In the screencast, we mention the two proposed theories for the mechanics of scent recognition; vibration theory and shape theory (or the lock and key model). The mechanics …

Chemical Attraction and Organic Compounds

Although chemists come from different countries and speak different languages, they all understand chemical formulae. For example, in methane – which has the chemical formula CH4 – it is important …