Want to keep learning?

This content is taken from the Taipei Medical University's online course, Pharmacokinetics: Drug Dosing in Renal Disease. Join the course to learn more.

Skip to 0 minutes and 11 seconds So if the patient in ARF their condition becomes very severe and we may need to use dialysis . There are a simple memory tips for you. That’s called AEIOU. A stands for Acid-base so when a patient has a severe metabolic acidosis. We can consider for dialysis. And for patient with E, electrolytes, severe hyperkalemia will be one of the indication for dialysis. And I as means the intoxication. So some patient they have medications induced ARF. And some of list are actually removable by dialysis such as salicylate, theophylline, phenobarbital and we can consider to have a dialysis for the patient.

Skip to 1 minute and 18 seconds And O as for fluid overload so if the patient has intravascular volume overload those patients can start on dialysis to quickly remove their fluid. Otherwise, when you put those patient on diuretics it probably too slow to avoid those fluid overload. And last but the least is uremia. And uremia if the patient has clinical evidence of uremia and those patient can use dialysis. And so prophylactic dialysis of a patient has very high BUN or creatine. We can serve the patient on dialysis. So summary of ARF treatment. First of all, prevention is always the best.

Skip to 2 minutes and 20 seconds So prevention nephrotoxicity to avoid take those medication, with high incidence of nephrotoxicity in high-risk patient or using correct dose and do closely blood level check and continually changing their dose accordingly. Yes, very important And when the patient start with ARF. We need to have a clear diagnosis about the types and the cause of ARF and treat those underlying diseases carefully. And if those patient has established ARF supportive measure as important and then we can actually let those patients kidney to fight on their own. And treat underlying diseases specific to pre, intrinsic or post renal ARF are very important. And finally if the patient develop complication.

Skip to 3 minutes and 35 seconds We need to manage those complications and if those patient is actually in very severe ARF using dialysis as very important skill to help the patient overcome ARF. Now we finish this lecture and thank you for participating this lesson. And I hope you enjoy your learning here. Thank you.

Indications for Dialysis in ARF & Summary

In this step, Prof. Chen clarifies the indications for dialysis in ARF, and gives the summary of this week.

To begin with, there are five main indications, including acid/base, electrolytes, intoxications, fluid overload, and uremia, called AEIOU.

Besides, for ARF treatment, prevention is always the best. Preventing nephrotoxicity from taking those medication is the first priority.

If the patient starts with ARF, we need to have a clear diagnosis about the types and the cause, then treat those underlying diseases specific to pre, intrinsic or post renal ARF carefully.

If we have suitable ARF supportive measures, we can let them fight on their own. Finally, check whether the patient develops complication or not.

This is the final video of this week. Please reflect upon the example that the professor used, and feel free to leave a comment that you think most useful or impressed. We hope you enjoy your learning.

Share this video:

This video is from the free online course:

Pharmacokinetics: Drug Dosing in Renal Disease

Taipei Medical University