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Tobramycin Dosing Regimen : Example 2

Tobramycin Dosing Regimen : Example 2

In this video, Prof. Lee demonstrates the steps to estimate the dosing regimen of Tobramycin.

To begin with, we can see that in the first diagram, the y-axis is the percent of normal dosage (%), and the x-axes are creatinine clearance (mL/min/1.73m2) and serum creatinine (mg/100mL).

Following that, we need to understand the steps to solve the question in the example: first, we should use the ideal body weight formula to get his IBW; secondly, estimate his creatinine clearance by C-G equation. Thirdly, predict the half-life of tobramycin for this patient.

Ultimately, we will read the dosing regimen from the table on the final slide.

Do you have any questions about the example2? Please leave them below.

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Pharmacokinetics: Drug Dosing in Renal Disease

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