Prof. Mary Ferrill clarifies grading in CPGs and major inconsistencies in this video. To begin with, there are 5 grades or levels in total. Firstly, the studies in GRADE A …
Prof. Mary Ferrill gives an example to clarify how to choose an appropriate CPG. We are given a topic on the treatments of nausea and vomiting in pregnancy, and we …
Prof. Mary Ferrill shows the CPG search strategy in this video. To begin with, there are many therapeutic disease states, such as UTIs (urinary tract infections). If we want to …
Prof. Mary Ferrill gives a brief introduction to clinical practice guidelines (CPG) and the learning objectives for this lesson. To begin with, it is very important for us to be …
During this week, we discuss the FACTS of noninferiority trials. Here is an article recommended for you. Simplifying and interpreting the FACTS of noninferiority trials: A stepwise approach When assessing …
Prof. Mary Ferrill demonstrates important principles and concludes this week. Again, we are reminded to use the FACTS to evaluate the studies. What we are supposed to do is to …
Prof. Mary Ferrill gives three examples to make sure that we are able to apply the knowledge on studies. She starts this video with three questions. Can superiority be concluded …
Prof. Mary Ferrill clarifies how to compare ITT and Per Protocol and how to translate CIs graphically. First, remember ITT means intention to treat, and the traditional definition is that …
Prof. Mary Ferrill explains how to evaluate P values, power, and mainly the NI margin in this video. When interpreting P values in NI, we have to keep in mind …
Prof. Mary Ferrill gives a clear illustration of how to analyze an Non-Inferiority (NI) trial. To begin with, we have to learn the differences between superiority and non-inferiority. In addition, …
Prof. Mary Ferrill lists the learning objectives for this lesson and gives a brief introduction. There are nine objectives for this lesson, including formulating a null hypothesis for a noninferiority …
In this article, the author explore the factors (beyond the efficacy of a therapy) that influence the number needed to treat and that must be taken into account when comparing …
Prof. Mary Ferrill gives a summary of this lesson. Continuing from the previous video, we can find the confidence intervals in this example are extremely wide, which indicates the data …
In this video, Prof. Mary Ferrill continues to explain RR, RRR (Relative RIsk Reduction), ARR (Absolute Risk Reduction), and NNT/NNH in the clinical trial. We are given an example from …
Prof. Mary Ferrill explains how to calculate RR, RRR (Relative RIsk Reduction), ARR (Absolute Risk Reduction), and NNT/NNH. She starts this video with a table about the exposure and outcome …