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Building a workflow on Galaxy

By now, you are becoming familiar with the concepts of loading up an input file into Galaxy, performing a task with that file, and saving the output of this task. …

What is bioinformatics?

Paulien Hogeweg and Ben Hesper described for the first time the term bioinformatics as “the study of informatics processes in biotic systems”. In a very simplistic way, bioinformatics could be …

Variant calling tutorial

In this tutorial, you will be using DeepVariant on the Galaxy platform for calling SNVs in a SARS-CoV-2 genomic sample followed by variant annotation using snpEff. The test dataset for …

SARS-CoV-2 replication cycle

In this video, you will be guided through the SARS-CoV-2 replication cycle. You will learn how the virus enters the cells and cause disease and details of how the virus …

Using existing workflows on Galaxy

In this step, you are going to learn how to import publicly available Galaxy workflows and execute them. This workflow was edited from the original workflow available on Galaxy to …

Processing data on Galaxy

In this step, you will learn how to process your data on Galaxy using NanoPlot to assess the quality of the FASTQ files. There are some files for download if …

Importing data onto Galaxy

In this tutorial, you are going to learn how to access the Australian Galaxy server and upload data onto your account. If you would like to try and test this …

Ownership of analyses tools and pipelines

Bioinformatics provides tools to catalogue, analyse and manage biological research data and information, through tools like algorithms, databases and software. Accessibility to these tools is essential for the advancement of …

Metadata: standardisation and colection tools

Click here to enlarge the image Figure 1 – An interesting-looking graph with incomplete labelling. Source: Hugh Fox III Imagine coming across this interesting-looking graph in Figure 1 above, but …

Ethics in data sharing

Over the past two decades, major advances in the molecular, cell biology and biotechnology research fields can be attributed to the pooled efforts of research teams and consortiums globally. Much …

The importance of sample and data consent

The major threat to global public health that SARS-CoV2 presented led to an unprecedented pace of much-needed research and vaccine development. This simultaneously meant the acceleration of ethical procedures that …

Quality control in phylogenetics

Even though there are different quality control (QC) steps followed before performing the phylogeny, there are several factors that influence the SARS-CoV-2 phylogenies and will be a bottleneck to interpreting …

Introduction to phylogenetics: tools and models

Within the first year of the coronavirus disease 2019 (COVID-19) pandemic, almost 400,000 whole or partial severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes were generated and shared openly, marking …