Course Q & A
After the course has run for 4 weeks Professor Rick Dunn will answer questions from the course. A video of the Q&A will be uploaded to the course in the …
Course: Metabolomics: Understanding Metabolism in the 21st Century
Course summary
Congratulations on completing the course. We hope that you enjoyed it. Take this opportunity to review any parts of the course and watch the film presented by Professor Mark Viant …
Metabolite Identification Databases
In the metabolite identification or annotation process parameters from our experimental data are matched to databases. This may be the mass or the fragmentation mass spectra of a metabolite. There …
Metabolite identification and databases
Dr Ralf Weber provides an overview of metabolite annotation and identification and describes the approaches that are applied to increase our confidence in the identification of metabolites through the use …
The challenge of identifying metabolites
To convert data to biological knowledge we have to annotate or chemically identify metabolites highlighted in the data analysis. Throughout the course we have discussed that metabolomes are highly complex …
Multivariate statistical analysis
Drs Jasper Engel introduces the multivariate data analysis approaches that are applied in the analysis of metabolomics data.
Introduction to the application of univariate data analysis in metabolomics
Drs Jasper Engel introduces the univariate data analysis approaches that are applied in the analysis of metabolomics data.
Deconvolution: current challenges and the best tools
Data processing is the computational process of converting raw LC-MS data to biological knowledge and involves multiple processes including raw data deconvolution and the chemical identification of metabolites. The process …
Introduction to Week 4
Dr Ralf Weber introduces the topics that will be covered in the final week of the course. If you have joined the course in September and want to post questions …
Liquid chromatography-mass spectrometry data processing
Professor Warwick Dunn introduces the approaches that are applied to process the raw data files produced in liquid chromatography-mass spectrometry to produce a data matrix.
Direct infusion mass spectrometry data processing
Dr Ralf Weber provides an overview of the approaches applied to process the raw data files produced in direct infusion mass spectrometry.
Analytical Techniques applied in Metabolomics
There is a range of analytical chemistry instruments applied in metabolomics research with some being applied frequently and routinely whereas others have specific roles and are used less frequently. Each …
Liquid chromatography-mass spectrometry
Liquid chromatography mass spectrometry is widely used in the metabolomics field to analyse biological samples. Chromatography provides partial or complete separation of metabolites prior to separation by mass spectrometry. Professor …
Direct infusion mass spectrometry
Professor Mark Viant describes the application of direct infusion mass spectrometry to analyse the metabolome of biological samples and explains how scientists at the University of Birmingham are optimising the …
These articles are from the online course:
Metabolomics: Understanding Metabolism in the 21st Century
