Skip main navigation

Course Q & A

After the course has run for 4 weeks Professor Rick Dunn will answer questions from the course. A video of the Q&A will be uploaded to the course in the …

Course summary

Congratulations on completing the course. We hope that you enjoyed it. Take this opportunity to review any parts of the course and watch the film presented by Professor Mark Viant …

Developing metabolite identification pipelines

In the metabolite identification or annotation process parameters from our experimental data are matched to databases. This may be the mass or the fragmentation mass spectra of a metabolite. There …

Metabolite identification and databases

Dr Ralf Weber provides an overview of metabolite annotation and identification and describes the approaches that are applied to increase our confidence in the identification of metabolites through the use …

The challenge of identifying metabolites

To convert data to biological knowledge we have to annotate or chemically identify metabolites highlighted in the data analysis. Throughout the course we have discussed that metabolomes are highly complex …

Deconvolution: current challenges and the best tools

Data processing is the computational process of converting raw LC-MS data to biological knowledge and involves multiple processes including raw data deconvolution and the chemical identification of metabolites. The process …

Introduction to Week 4

Dr Ralf Weber introduces the topics that will be covered in the final week of the course. If you have joined the course in September and want to post questions …

Analytical Techniques applied in Metabolomics

There is a range of analytical chemistry instruments applied in metabolomics research with some being applied frequently and routinely whereas others have specific roles and are used less frequently. Each …

Liquid chromatography-mass spectrometry

Liquid chromatography mass spectrometry is widely used in the metabolomics field to analyse biological samples. Chromatography provides partial or complete separation of metabolites prior to separation by mass spectrometry. Professor …

Direct infusion mass spectrometry

Professor Mark Viant describes the application of direct infusion mass spectrometry to analyse the metabolome of biological samples and explains how scientists at the University of Birmingham are optimising the …