Course: Metabolomics: Understanding Metabolism in the 21st Century

After the course has run for 4 weeks Professor Rick Dunn will answer questions from the course. A video of the Q&A will be uploaded to the course in the …

Congratulations on completing the course. We hope that you enjoyed it. Take this opportunity to review any parts of the course and watch the film presented by Professor Mark Viant …

In the metabolite identification or annotation process parameters from our experimental data are matched to databases. This may be the mass or the fragmentation mass spectra of a metabolite. There …

Dr Ralf Weber provides an overview of metabolite annotation and identification and describes the approaches that are applied to increase our confidence in the identification of metabolites through the use …

To convert data to biological knowledge we have to annotate or chemically identify metabolites highlighted in the data analysis. Throughout the course we have discussed that metabolomes are highly complex …

Drs Jasper Engel introduces the multivariate data analysis approaches that are applied in the analysis of metabolomics data.

Drs Jasper Engel introduces the univariate data analysis approaches that are applied in the analysis of metabolomics data.

Data processing is the computational process of converting raw LC-MS data to biological knowledge and involves multiple processes including raw data deconvolution and the chemical identification of metabolites. The process …

Dr Ralf Weber introduces the topics that will be covered in the final week of the course. If you have joined the course in September and want to post questions …

Professor Warwick Dunn introduces the approaches that are applied to process the raw data files produced in liquid chromatography-mass spectrometry to produce a data matrix.

Dr Ralf Weber provides an overview of the approaches applied to process the raw data files produced in direct infusion mass spectrometry.

Dr Warwick Dunn responds to your questions from Week 3.

Liquid chromatography mass spectrometry is widely used in the metabolomics field to analyse biological samples. Chromatography provides partial or complete separation of metabolites prior to separation by mass spectrometry. Professor …

Professor Mark Viant describes the application of direct infusion mass spectrometry to analyse the metabolome of biological samples and explains how scientists at the University of Birmingham are optimising the …